Review Article
 
Anaesthesia in patients with renal failure
Alice Myers1, Zoka Milan2
1Consultant in Anaesthesia and Intensive Care Medicine, Department of Anaesthesia, East Surrey Hospital, UK
2Consultant Anaesthetist, Honorary Senior Lecturer, Visiting Professor, Department of Anaesthesia, King’s College Hospital, London, UK

Article ID: 100015A05AM2018
doi: 10.5348/100015A05AM2018RA

Corresponding Author:
Alice Elizabeth Myers,
1 Marlborough Mews,
Brixton, London, SW2 5TE

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How to cite this article
Myers A, Milan Z. Anaesthesia in patients with renal failure. Edorium J Anesth 2018;4:100015A05AM2018.


ABSTRACT

Anaesthetists need a working understanding of the implications of renal impairment for the safe conduct of anaesthesia. Patients with renal failure are often encountered when managing elective or emergency surgical cases. In addition, it is fundamental to consider how kidney injury frequently forms part of the clinical picture during resuscitation and optimisation of acutely unwell patients in the emergency department or critical care. The functions of the kidney are multiple, and beyond the scope of this paper. The aim of this review is to summarise current classifications of renal impairment and explore the evidence underpinning relevant practice in anaesthesia. Patient groups include those with chronic renal failure, patients with acute renal failure, and also patients with normal preoperative renal function but who have a high risk of developing peri-operative kidney injury. There is a dearth of strong evidence to guide anaesthetic practice with regards to renal failure. As a result, many of the studies quoted here are small cohorts, case series, or case reports. In general, anaesthetists are still mainly guided by their knowledge of physiology, pharmacology and pathology to safely manage patients with kidney injury.

Keywords: Acute kidney injury, Anaesthesia, Chronic kidney injury


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Author Contributions
Alice Myers – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Zoka Milan – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of Submission
The corresponding author is the guarantor of submission.
Source of Support
None
Conflict of Interest
Author declares no conflict of interest.
Copyright
© 2018 Alice Myers et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.